NFL odds Week 1: Lines for every game, picks, results

The first Sunday of the season is finally here so how are you faring on your wagers?

Here is everything you need to know about the NFL odds for Week 1 — the point spread, moneyline, total over/under for every game and picks by FOX Sports betting analyst Jason McIntyre (with all NFL odds via FOX Bet).

Can Dak Prescott lead this year’s Cowboys to a Super Bowl? | UNDISPUTED

The Cowboys have sky-high expectations and it all comes down to Dak.

From gambling-friendly schedules featuring live, updating odds to expert analysis and the day’s most-bet games, check out the all-new “NFL Odds” section on the FOX Sports App and FOXSports.com!

The defending Super Bowl champion Los Angeles Rams and 2021 Offensive Player of the Year, wide receiver Cooper Kupp, opened the season by taking an L to quarterback Josh Allen and the Super Bowl favorites, the Buffalo Bills. Will the remaining nine home underdogs fare any better?

Tom Brady and the Tampa Bay Buccaneers finish off Sunday’s slate of games by playing at the Dallas Cowboys. This powerhouse matchup should be a fun one to watch and gamble on.

Week 1 wraps up with the Denver Broncos and new quarterback Russell Wilson traveling to Seattle to take on Wilson’s former team, the Seahawks, on Monday Night Football.

Here are the updated Week 1 lines and betting results for every game (via FOX Bet): 

WEEK 1 GAMES 
* odds updated as of 9/11/2022

New York Giants @ Tennessee Titans (4:25 p.m. ET Sunday, FOX)

Point spread: Titans -5.5 (Titans favored to win by more than 5.5 points, otherwise Giants cover)
Moneyline: Titans -278 favorites to win (bet $10 to win $13.60 total); Giants +205 underdogs to win (bet $10 to win $30.50 total)
Total scoring over/under: 44 points scored by both teams combined

New York Giants

NYG

Tennessee Titans

TEN

RELATED: How to Bet Giants-Titans

McIntyre: “I’m not a trend bettor, but one worth looking at in Week 1: Teams that didn’t make the playoffs last season against teams that did. Like it or not, the prior year’s playoff team tends to be overvalued in the market.

“When it comes to this matchup, the Titans were the No. 1 seed in the AFC last year. On the flip side, the Giants were one of the league’s biggest dumpster fires, and they fired their coach.

“I like New York’s new coach, Brian Daboll, and think he will be a tremendous value add to struggling QB Daniel Jones. The Giants will be undervalued with a full arsenal of healthy weapons — like Saquon Barkley and Kenny Golladay — in September.

“Getting nearly a touchdown in this spot is too good to pass up.”

PICK: Giants (+6.5 at FOX Bet at time of pick) to lose by fewer than 6.5 points (or win outright)

Green Bay Packers @ Minnesota Vikings (4:25 p.m. ET Sunday, FOX)

Point spread: Vikings -1.5 (Vikings favored to win by more than 1.5 points, otherwise Packers cover)
Moneyline: Vikings -138 favorites to win (bet $10 to win $17.25 total); Packers +110 underdogs to win (bet $10 to win $22 total)
Total scoring over/under: 46.5 points scored by both teams combined

Green Bay Packers

GB

Minnesota Vikings

MIN

RELATED: How to Bet Packers-Vikings

Kansas City Chiefs @ Arizona Cardinals (4:25 p.m. ET Sunday, CBS)

Point spread: Chiefs -6 (Chiefs favored to win by more than 6 points, otherwise Cardinals cover)
Moneyline: Chiefs -278 favorites to win (bet $10 to win $13.60 total); Cardinals +205 underdogs to win (bet $10 to win $30.50 total)
Total scoring over/under: 53.5 points scored by both teams combined

Kansas City Chiefs

KC

Arizona Cardinals

ARI

RELATED: How to Bet Chiefs-Cardinals

Las Vegas Raiders @ Los Angeles Chargers (4:25 p.m. ET Sunday, CBS)

Point spread: Chargers -3.5 (Chargers favored to win by more than 3.5 points, otherwise Raiders cover)
Moneyline: Chargers -182 favorites to win (bet $10 to win $15.49 total); Raiders +140 underdogs to win (bet $10 to win $24 total)
Total scoring over/under: 52.5 points scored by both teams combined

Las Vegas Raiders

LV

Los Angeles Chargers

LAC

RELATED: How to Bet Raiders-Chargers

Tampa Bay Buccaneers @ Dallas Cowboys (8:20 p.m. ET Sunday, NBC)

Point spread: Buccaneers -2.5 (Buccaneers favored to win by more than 2.5 points, otherwise Cowboys cover)
Moneyline: Buccaneers -143 favorites to win (bet $10 to win $16.99 total); Cowboys +110 underdogs to win (bet $10 to win $21 total)
Total scoring over/under: 50.5 points scored by both teams combined

Tampa Bay Buccaneers

TB

Dallas Cowboys

DAL

RELATED: How to Bet Buccaneers-Cowboys

Denver Broncos @ Seattle Seahawks (8:15 p.m. ET Monday, ABC/ESPN)

Point spread: Broncos -6.5 (Broncos favored to win by more than 6.5 points, otherwise Seahawks cover)
Moneyline: Broncos -303 favorites to win (bet $10 to win $13.30 total); Seahawks +225 underdogs to win (bet $10 to win $32.50 total)
Total scoring over/under: 44.5 points scored by both teams combined

Denver Broncos

DEN

Seattle Seahawks

SEA

RELATED: How to Bet Broncos-Seahawks

COMPLETED GAMES

Pittsburgh Steelers 23, Cincinnati Bengals 20 (OT)

Point spread: Steelers (+7) cover by winning outright
Moneyline: Steelers win as +240 underdogs (bet $10 to win $34 total); Bengals were -333 favorites (bet $10 to win $13 total)
Total scoring over/under: Under 44.5 points scored by both teams combined (43)

Pittsburgh Steelers

PIT

Cincinnati Bengals

CIN

RELATED: How to Bet Steelers-Bengals

FOX Bet’s Jason McIntyre: “Mike Tomlin as an underdog in a division game? Take my money. The Bengals will be the most overvalued team in the market next season. Yes, they have an elite QB/WR combo in Joe Burrow and Ja’Marr Chase, but let’s also remember this team faced the third-easiest schedule in the NFL last season.

“The Bengals will now face the seventh-most difficult schedule when looking at the opponent’s season win totals. Bengals fans can earmuff the rest; everyone else, listen closely. Cincinnati held on to beat the Raiders when they failed inside the 10-yard line on fourth down. The Bengals beat the Titans on a walk-off field goal and then beat the Chiefs in overtime despite KC getting the ball first. If they don’t win all three of those games, Pittsburgh is probably closer to +3 or +3.5.

“This line is inflated. Give me the extra points.”

PICK: Steelers (+7) to lose by fewer than 7 points (or win outright) WIN

Cleveland Browns 26, Carolina Panthers 24

Point spread: Browns (+2) cover by winning outright
Moneyline: Browns win as +100 underdogs (bet $10 to win $20 total); Panthers were -125 favorites (bet $10 to win $18 total); 
Total scoring over/under: Over 42 points scored by both teams combined (50)

Cleveland Browns

CLE

Carolina Panthers

CAR

RELATED: How to Bet Browns-Panthers

New Orleans Saints 27, Atlanta Falcons 26

Point spread: Saints -5.5 (Saints favored to win by more than 5.5 points, otherwise Falcons cover)
Moneyline: Saints -250 favorites to win (bet $10 to win $14 total); Falcons +190 underdogs to win (bet $10 to win $29 total)
Total scoring over/under: 43.5 points scored by both teams combined

New Orleans Saints

NO

Atlanta Falcons

ATL

RELATED: How to Bet Saints-Falcons

NOTES: Will Lutz‘s 51-yard field goal with 19 seconds to go helped New Orleans rally from a 16-point deficit in the fourth quarter. … Saints quarterback Jameis Winston was 13-for-16 passing (with two intentional spikes) for 212 yards and two touchdowns in the period.

Philadelphia Eagles 38, Detroit Lions 35

Point spread: Lions (+5.5) cover by losing by fewer than 5.5 points (3)
Moneyline: Eagles win as -250 favorites (bet $10 to win $14 total); Lions were +190 underdogs (bet $10 to win $29 total)
Total scoring over/under: Over 48 points scored by both teams combined (73)

RELATED: How to Bet Eagles-Lions

Baltimore Ravens 24, New York Jets 9

Point spread: Ravens (-6.5) covers by winning by more than 6.5 points (15)
Moneyline: Ravens win as -303 favorites (bet $10 to win $13.30 total); Jets ware +220 underdogs (bet $10 to win $32 total)
Total scoring over/under: Under 44 points scored by both teams combined (33)

Baltimore Ravens

BAL

New York Jets

NYJ

RELATED: How to Bet Ravens-Jets

Miami Dolphins 20, New England Patriots 7

Point spread: Dolphins (-3) cover by winning by more than 3 points (13)
Moneyline: Dolphins win as -162 favorites (bet $10 to win $16.15 total); Patriots were +125 underdogs (bet $10 to win $22.50 total)
Total scoring over/under: Under 46.5 points scored by both teams combined (27)

New England Patriots

NE

Miami Dolphins

MIA

RELATED: How to Bet Patriots-Dolphins

Chicago Bears 19, San Francisco 49ers 10

Point spread: Bears (+6.5) cover by winning outright
Moneyline: Bears were +220 underdogs (bet $10 to win $32 total); 49ers were -303 favorites (bet $10 to win $13.30 total)
Total scoring over/under: Under 37 points scored by both teams combined (29)

San Francisco 49ers

SF

Chicago Bears

CHI

RELATED: How to Bet 49ers-Bears

Jacksonville Jaguars 28, Washington Commanders 22

Point spread: Commanders (-3) cover by winning by more than 3 points (6)
Moneyline: Commanders win as -162 favorites (bet $10 to win $16.17 total); Jaguars were +125 underdogs (bet $10 to win $22.50 total)
Total scoring over/under: Over 43.5 points scored by both teams combined (50)

Jacksonville Jaguars

JAX

Washington Commanders

WAS

RELATED: How to Bet Jaguars-Commanders

Indianapolis Colts 20, Houston Texans 20 (OT)

Point spread: Texans (+7) cover by playing to a tie
Moneyline: Colts were -400 favorites (bet $10 to win $12.50 total); Texans were +280 underdogs  (bet $10 to win $38 total)
Total scoring over/under: Under 46 points scored by both teams combined (40)

Indianapolis Colts

IND

Houston Texans

HOU

RELATED: How to Bet Colts-Texans

Buffalo Bills 31, Los Angeles Rams 10

Point spread: Bills (-2) cover by winning by more than 2 points (21)
Moneyline: Bills win as -138 favorites (bet $10 to win $17.25 total); Rams were +115 underdogs (bet $10 to win $21.50 total)
Total scoring over/under: Under 52 points scored by both teams combined (41)

Buffalo Bills

BUF

Los Angeles Rams

LAR

If you are betting on this week’s NFL slate, check out these posts below because we have you covered from every possible angle!

Warren Sharp gives you his sharpest betting edges for Week 1

Our Insider Patrick Everson breaks down all the hot, bigmoney chatter from Las Vegas

This week’s card features a record number of home underdogs. Read which dogs Jason McIntyre thinks have a chance to bark.

Geoff Schwartz’s best wagers 

Jason McIntyre’s favorite bets

Sammy P’s sharp college football and NFL wagers

Our experts’ Super Bowl picks

Looking for even more NFL content? Head over to the NFL section on the FOX Sports app and website for all the latest news, and make sure to favorite the NFL and your favorite team — or teams! — while you’re there.


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